Cyklokapron - Tranexamic Acid 250/500mg
Cyklokapron belongs to a class of anti-fibrinolytics, it contains Tranexamic acid, which prevent and stop prolonged bleeding. This medication is indicated in patients with bleeding disorder (hemophilia) to reduce or prevent hemorrhage. It is also used to control bleeding after surgery or an injury, during heavy nosebleeds, or during menstruation.
Usage.
Cyklokapron injection 100 mg/ml. Cyklokapron 50 mg tablets.
NDC 0013-1114-10 10 x 10 ml ampules.
Dosage depends on your weight, your medical condition and response to treatment. As usual it takes 2 to 4 times daily by mouth.
The best effect is achieved if Cyklokapron used regular. Do not increase your dose; do not change the treatment regimen.
Before tooth extraction in patients with hemophilia prescribe 10 mg /kg body mass Cyklokapron intravenously together with replacement therapy.
After tooth extraction, intravenous therapy, at a dose of 10 mg/kg body weight three to four times daily, may be used for 2 to 8 days.
After intravenous administration the concentration decreased gradually for 6 hours, half-life is 3 hours; volume of distribution is 33% of body weight.
It is very important to know that this medication should not be injected more rapidly than 1 ml per minute, because hypotension can be occurred.
Overdose.
In case of overdose gastrointestinal, hypertensive, visual impairment; convulsions, mental status changes; myoclonus, and rash side effects can occur.
If you have such problems contact to your doctor.
Side effects.
Most people using Cyklokapron do not have serious side effects. But it does not mean that Cyklokapron is safe for your health.
Possible side effects:
- gastrointestinal disturbances (nausea, vomiting, dizziness, diarrhea)
- coughing up blood
- giddiness
- fainting
- pain in the arms and legs
- confusion and slurred speech
- weakness
- vision changes
- allergic reaction (dermatitis)
If you have any of these side effects, especially if they worsen, tell your doctor immediately. In most cases you need to change the dose.
Interaction.
Solution of Cyklokapron should not be mixed with blood products and solutions containing penicillin.
For intravenous infusion Cyklokapron may be added in most solutions (electrolyte solutions, carbohydrate solutions, amino acid solutions, dextran solutions), heparin also can be added.
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